Chronic inflammatory diseases of the larynx (CIAG) are a collective concept of a fairly large number of diseases with different etiologies. Nosological forms of diseases of the larynx are presented in a wide range - from functional disorders leading to respiratory failure, benign formations of the larynx to severe, long-term cicatricial stenoses that require complex reconstructive operations.

The article compares the effect of standard treatments containing gliflozins, i.e. glucose sodium cotransporter type 2 inhibitor dapagliflozin (forsiga) on hematological changes, intracardiac hemodynamics, kidney function, in particular glomerular filtration rate and collagen Ⅳ indicators in urine in patients with chronic heart failure anemia studied. The increase in erythropoietin levels in the group of patients who received dapagliflozin after treatment is related to the effect of the drug on stimulating the production of erythropoietin in the kidney. It is also confirmed that the effective reduction of the amount of collagen Ⅳ in the urine after the treatment has an effective effect of the drug on the fibrosis processes in the kidney.

This article analyzes and discusses the topic of ambulatory blood pressure monitoring in women with ischemic stroke.

This article discusses the clinical features of ischemic stroke in patients with type II diabetes. It should be noted that type II diabetes mellitus (DM 2) is one of the main risk factors and has a special place among all diseases that lead to stroke. The role of DM 2 in the development of the first stroke was presented as a result of a 10-year follow-up in Framingham (USA). A population study of people aged 55-84 years showed that people with diabetes have a significantly higher rate of death from stroke.

In the period after tympanoplasty surgery, certain clinical morphological processes take place in the tympanic cavity, tympanic membrane, and external auditory canal, and the mucus layer of the tympanic cavity is restored, the permeability and barofunction of the auditory canal are restored. This process continues for a long time, and the transplants restore their optimal functional state. In our observation, morphological changes in the tympanic membrane, tympanic cavity, and external auditory canal lasted from 1 to 6 months. Therefore, it is important to observe morphological changes in the tympanic membrane and study functional changes.

The article presents a comparative description of the results of treatment of patients with pre-stroke cerebrovascular disorders in hypertension. Among the problems of modern otorhinolaryngology, one of the leading places belongs to cochleovestibular disorders in some cardiovascular diseases, in particular, hypertension. The state of vestibular function in arterial hypertension was studied by many authors who noted a decrease in resistance in such patients.

In the article, the effect of standard treatments containing gliflozin, i.e. glucose sodium cotransporter type 2 inhibitor dapagliflozin-forsi, on kidney function in particular on glomerular filtration rate and collagen Ⅳ indicators in urine, was studied in the article. In the group of patients who received dapagliflozin, a significant decrease in the amount of collagen Ⅳ in urine after the first month of treatment confirmed the effective effect of the drug on fibrosis processes in the kidney.

Violation of the integrity of the main barrier of protection - the mucous membrane - leads to the development of its inflammation. Thus, at the moment it is quite convincingly established that fungi can be, and are, the main cause of inflammation of the mucous membrane of the upper respiratory tract. This thesis does not remove the importance of viral and bacterial infection as the cause of inflammation. Any infectious agent encounters a powerful obstacle in the form of normal mucociliary transport. As long as mucociliary transport is functioning normally, the inflammatory agent has no opportunity to come into contact with cell receptors and cause disease. In this regard, any treatment must take into account the effect of the method or drug on mucociliary transport. Agents that damage mucociliary transport should not be used, and surgical methods should minimally damage the mucosa.

This article discusses the dynamics of coagulation hemostasis indicators in patients with ischemic stroke depending on the status of Covid-19. To date, according to a review of the literature, there is no consensus regarding anticoagulant and antiplatelet prevention of cerebrovascular complications in COVID-19.

This article analyzed and discussed the topic of acute disorders of cerebral blood circulation against the background of post-covid syndrome.

In the practical work of an otolaryngologist, clinical cases are often observed when there is an acute need for plastic materials to restore the integrity of the tympanal and neotympanal membranes. For this purpose, surgeons often began to use the following materials: fascia of the temporal muscle, inguinal and inguinal membrane, periosteum, nasal septum and lung mucosa, vein wall, amniotic membrane, polymer implants, two- and three-layer grafts. One of the urgent problems of otiatrics of great social importance is to restore the integrity of the sound transmission system in patients with chronic inflammatory diseases of the middle ear. Chronic otitis media and some of its possible complications: paresis of the facial nerve, hearing loss, severe autogenic intracerebral complications, and obvious social disadaptation of patients occupy a leading position in the diseases of the ENT organs, while the surgical treatment methods used in the treatment of this pathology are always does not give a chance to achieve satisfactory results.